Publications

Welcome to our Publications Page, a dedicated space where we share a collection of our scientific peer-reviewed publications. 

Here, you will find a comprehensive array of research that reflects our therapy areas, commitment to advancing knowledge and innovation. 

We aim to make these valuable resources accessible to researchers, students, and inquisitive minds alike, fostering a community driven by curiosity and discovery. 

Explore, engage, and join us in our journey toward a brighter, more informed future.

Title Date Publication title Category Link to publications
Model-Informed Approaches and Innovative Clinical Trial Design for Adeno-Associated Viral Vector-based Gene Therapy Product Development - A White Paper Clinical Pharmacology & Therapeutics R&D/Discovery
Innate immune activation and aberrant function in the R6/2 mouse model and Huntington's disease iPSC-derived microglia Frontiers in Molecular Neuroscience Neurology
Development and validation of a liquid chromatography-triple quadrupole mass spectrometry method for the determination of isopeptide ε-(γ-glutamyl) lysine in human urine as biomarker for transglutaminase 2 cross-linked proteins Journal of Chromatography A R&D/Discovery
European Medicinal Chemistry Leaders in Industry (EMCL) - On the Status and Future of Medicinal Chemistry Research in Europe ChemMedChem R&D/Discovery
Physician- and patient-reported perspectives on myasthenia gravis in Europe: A real-world survey Orphanet Journal of Rare Diseases Neurology
Impact of fragility fractures on activities of daily living and productivity in community-dwelling women: A multi-national study Osteoporosis International Bone
Development and validation of a liquid chromatography-triple quadrupole mass spectrometry method for the determination of isopeptide ε-( γ-glutamyl) lysine in human urine as biomarker for transglutaminase 2 cross-linked proteins Journal of Chromatography A R&D/Discovery
Mapping Relevance of Digital Measures to Meaningful Symptoms and Impacts in Early Parkinson’s Disease Journal of Parkinson's Disease Neurology
Deconstructing allostery by computational assessment of the binding determinants of allosteric PTP1B modulators Communications Chemistry R&D/Discovery
European Medicinal Chemistry Leaders in Industry (EMCL) – On the Status and Future of Medicinal Chemistry Research in Europe ChemMedChem R&D/Discovery
Divergent functional outcomes of NLRP3 blockade downstream of multi-inflammasome activation: Therapeutic implications for ALS Frontiers in Immunology Immunology
Technical considerations for the implementation of the Multi-Attribute-Method by mass spectrometry in a Quality Control laboratory European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V R&D/Discovery
Current State and Opportunities with Long-acting Injectables: Industry Perspectives from the Innovation and Quality Consortium "Long-Acting Injectables" Working Group Pharmaceutical Research R&D/Discovery
Phage Display of Bovine Ultralong CDRH3 Methods in Molecular Biology R&D/Discovery
Mortality following fragility hip fracture in China: A record linkage study Archives of Osteoporosis Bone
Hybrid controlled clinical trials using concurrent registries in Amyotrophic Lateral Sclerosis: A feasibility study Clinical Pharmacology & Therapeutics Neurology
Development and Assessment of an Artificial Intelligence-Based Tool for Ptosis Measurement in Adult Myasthenia Gravis Patients Using Selfie Video Clips Recorded on Smartphones Digital Biomarkers Neurology
Intraparenchymal convection enhanced delivery of AAV to treat Mucopolysaccharidosis IIIC Journal of Translational Medicine R&D/Discovery
Technical considerations for the implementation of the Multi-Attribute Method by mass spectrometry in a Quality Control laboratory European Journal of Pharmaceutics and Biopharmaceutics R&D/Discovery
PK/PD and Bioanalytical Considerations of AAV-Based Gene Therapies: an IQ Consortium Industry Position Paper AAPS Journal R&D/Discovery