UCB on a Growth Path for a Decade+

UCB’s Decade+ of Growth: Elevating lives of people through our medicines

 

 

 

Disclaimer

This website contains forward-looking statements, including, without limitation, statements containing the words “potential”, “believes”, “anticipates”, “expects”, “intends”, “plans”, “seeks”, “estimates”, “may”, “will”, “continue” and similar expressions. These forward-looking statements are based on current plans, estimates and beliefs of management. All statements, other than statements of historical facts, are statements that could be deemed forward-looking statements, including estimates of revenues, operating margins, capital expenditures, cash, other financial information, expected legal, arbitration, political, regulatory or clinical results or practices and other such estimates and results. By their nature, such forward-looking statements are not guaranteeing future performance and are subject to known and unknown risks, uncertainties, and assumptions which might cause the actual results, financial condition, performance or achievements of UCB, or industry results, to be materially different from any future results, performance, or achievements expressed or implied by such forward-looking statements contained in this document.

Important factors that could result in such differences include but are not limited to: global spread and impacts of wars, pandemics and terrorism, the general geopolitical environment, climate change, changes in general economic, business and competitive conditions, the inability to obtain necessary regulatory approvals or to obtain them on acceptable terms or within expected timing, costs associated with research and development, changes in the prospects for products in the pipeline or under development by UCB, effects of future judicial decisions or governmental investigations, safety, quality, data integrity or manufacturing issues, supply chain disruption and business continuity risks; potential or actual data security and data privacy breaches, or disruptions of our information technology systems, product liability claims, challenges to patent protection for products or product candidates, competition from other products including biosimilars or disruptive technologies/business models, changes in laws or regulations, exchange rate fluctuations, changes or uncertainties in tax laws or the administration of such laws, and hiring,  retention and compliance of its employees. There is no guarantee that new product candidates will be discovered or identified in the pipeline, or that new indications for existing products will be developed and approved. Movement from concept to commercial product is uncertain; preclinical results do not guarantee safety and efficacy of product candidates in humans. So far, the complexity of the human body cannot be reproduced in computer models, cell culture systems or animal models. The length of the timing to complete clinical trials and to get regulatory approval for product marketing has varied in the past and UCB expects similar unpredictability going forward. Products or potential products which are the subject of partnerships, joint ventures or licensing collaborations may be subject to disputes between the partners or may prove to be not as safe, effective or commercially successful as UCB may have believed at the start of such partnership. UCB’s efforts to acquire other products or companies and to integrate the operations of such acquired companies may not be as successful as UCB may have believed at the moment of acquisition. Also, UCB or others could discover safety, side effects or manufacturing problems with its products and/or devices after they are marketed. The discovery of significant problems with a product similar to one of UCB’s products that implicate an entire class of products may have a material adverse effect on sales of the entire class of affected products. Moreover, sales may be impacted by international and domestic trends toward managed care and health care cost containment, including pricing pressure, political and public scrutiny, customer and prescriber patterns or practices, and the reimbursement policies imposed by third-party payers as well as legislation affecting biopharmaceutical pricing and reimbursement activities and outcomes. Finally, a breakdown, cyberattack or information security breach could compromise the confidentiality, integrity and availability of UCB’s data and systems.

Given these uncertainties, the public is cautioned not to place any undue reliance on such forward-looking statements. These forward-looking statements are made only as of the date of this document, and do not reflect any potential impacts from the evolving event or risk as mentioned above as well as any other adversity, unless indicated otherwise. The company continues to follow the development diligently to assess the financial significance of these events, as the case may be, to UCB.

UCB expressly disclaims any obligation to update any forward-looking statements in this document, either to confirm the actual results or to report or reflect any change in its forward-looking statements with regard thereto or any change in events, conditions or circumstances on which any such statement is based, unless such statement is required pursuant to applicable 
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Our key medicines

We bring solutions to people living with neurological or immunological diseases.

    Growth drivers

  • BIMZELX® (bimekizumab)

    BIMZELX® (bimekizumab)

    Reaching more than 49 700 patients globally (Dec 2024)

    Indications: Psoriasis (PSO); Psoriatic Arthritis (PsA); Ankylosing spondylitis (AS); non-radiographic Axial Spondyloarthritis (nr-axSpA)

    Loss of Exclusivity (indicative): 2035 in U.S., without patent term extension; 2036 in Europe, 2037 in Japan

    Sales: € 607 million in 2024

    Peak sales guidance: > € 4 billion

    BIMZELX® - prescribing information

  • EVENITY® (romosozumab)

    EVENITY® (romosozumab)

    Reached more than 900 000 patients globally since launch (Dec 2024)

    Indication: Osteoporosis

    Loss of Exclusivity (indicative): 2031 in Europe and Japan, 2033 in U.S.

    Sales: € 103 million in 2024 in Europe. Net sales outside Europe reported by Amgen and Astellas

    EVENITY® - prescribing information

  • FINTEPLA® (fenfluramine)

    FINTEPLA® (fenfluramine)

    Reaching more than 7 600 patients globally (Dec 2024)

    Indications: Dravet Syndrome, Lennox-Gastaut Syndrome. 

    Loss of Exclusivity (indicative). 2032 in Europe and Japan, 2033 in U.S.

    Sales: € 340 million in 2024.

    Peak sales guidance: € 800 million by 2027.

    FINTEPLA® - prescribing information

  • RYSTIGGO® (rozanolixizumab)

    RYSTIGGO® (rozanolixizumab)

    Launched in the U.S. in July 2023, approved and launched in Europe and Japan

    Indication: generalized Myasthenia Gravis.

    Loss of Exclusivity (indicative): 2033 in Japan. 2034 in Europe and 2035 in U.S., all without patent term extension.

    Sales: € 202 million in 2024.

    RYSTIGGO® - prescribing information

  • ZILBRYSQ® (zilucoplan)

    ZILBRYSQ® (zilucoplan)

    Global launches started April 2024

    Indication: generalized Myasthenia Gravis.

    Loss of Exclusivity (indicative): 2035 in Europe, Japan & U.S. without patent term extension.

    ZILBRYSQ® - prescribing information

  • Solid foundation

  • BRIVIACT® (brivaracetam)

    BRIVIACT® (brivaracetam)

    Reaching more than 230 000 patients globally (MAT Q3/20234)

    Indication: Epilepsy partial-onset seizure, also known as focal seizure

    Loss of Exclusivity (indicative): 2026 in Europe & U.S.

    Sales: € 686m in 2024, reaching its peak sales two years ahead of 2026

    Peak sales guidance: ≥ € 600 million by 2026

    BRIVIACT® - prescribing information

  • CIMZIA® (certolizumab pegol)

    CIMZIA® (certolizumab pegol)

    Reaching more than 180 000 patients globally (MAT Q3/2023)

    Indications: Ankylosing spondylitis (AS); non-radiographic Axial Spondyloarthritis (nr-axSpA); Crohn's disease (CD); Psoriasis (PSO); Psoriatic arthritis (PsA); Rheumatoid arthritis (RA)

    Loss of Exclusivity (indicative): 2024 in Europe & U.S. 2026 in Japan.

    Sales: € 2  033 million in 2024

    Peak sales guidance: ≥ € 2 billion by 2024 achieved in 2022

    AS - prescribing information
    nr-axSpA - prescribing information
    CD - prescribing information
    PSO - prescribing information
    PsA - prescribing information
    RA - prescribing information

  • KEPPRA® (levetiracetam)

    KEPPRA® (levetiracetam)

    Reaching more than 1.8 million patients globally (MAT Q3/2024)

    Indications: Epilepsy partial-onset seizures, also known as focal seizures; Epilepsy primary generalized tonic-clonic seizures; Epilepsy myoclonic seizures

    Loss of Exclusivity: U.S. - 2008, Europe - 2010, Japan - 2020.

    Sales: € 582 million in 2024

    Peak sales: € 1.2 billion (2008)

    KEPPRA® - prescribing information

  • NAYZILAM® (midazolam nasal spray)

    NAYZILAM® (midazolam nasal spray)

    Reaching more than 93 000 patients in the U.S. (As of December 2024)

    Indication: Epilepsy seizure clusters

    Loss of Exclusivity (indicative): 2028 in U.S.

    Sales: € 124 million in 2024

    NAYZILAM® - prescribing information

    Logo Nayzilam
  • VIMPAT® (lacosamide)
    Vimpat_logo

    VIMPAT® (lacosamide)

    Reaching more than 570 000 patients globally (MAT Q3/2024)

    Indications: Epilepsy partial-onset seizures, also known as focal seizures; Epilepsy primary generalized tonic-clonic seizures

    Loss of Exclusivity: 2022 in Europe & U.S. 2024 in Japan (indicative)

    Sales: € 329 million in 2023

    Peak sales: € 1.5 billion (2021)

    VIMPAT® - prescribing information



Our clinical development pipeline

UCB continuously innovates and strives to find new ways to deliver solutions to people living with severe immunological and neurological diseases, reflected in a clinical development pipeline encompassing now one phase 4 (post-approval) asset, one asset under regulatory review, four phase 3 projects, four phase 2 projects - addressing different patient populations.

General information

All medicines must pass safety and efficacy tests if they are to be approved by regulators. This is done through a series of rigorous clinical studies, also referred to as clinical trials, research studies or medical research.

Clinical studies index

UCB is committed to sharing information on studies and making study results publicly accessible. You will find below links to the clinical studies (Phase 2-4) of our main R&D projects.
 

Contact UCB IR Team

investor-relations@ucb.com or a specific team member:

Antje Witte, Head of Investor Relations
Tel: +32 2 559 9414
E-mail: Antje.Witte@ucb.com



Sahar Yazdian, Investor Relations Lead

Tel: +32 2 559 9137
E-mail: Sahar.Yazdian@ucb.com

UCB IR App