Levocetirizine (Xyzal®) Disease area studied Abbreviated title Phase Study ID Registry database Study results Plain language summary Publication (if available) Allergic Rhinitis Efficacy and Safety of Levocetirizine 8 Weeks Prior and After the Onset of the Grass Pollen Season in Subjects With SAR Phase 3 A00306 Completed NCT00521040 PDF Allergy Prevention of Asthma With Levocetirizine 18 Month Treatment in Infants (12 - 24 Months) Suffering From Eczema (Atopic Dermatitis) and Sensitized to Grass Pollen and/or House Dust Mite (HDM) Phase 3 A00309 Completed NCT00152464 LINKPDF Simons. Ann Allergy Asthma Immunol;2007;99(3);261-266. Allergy Efficacy and Safety of Levocetirizine for Treatment of Recurrent Cough Associated With Other Allergic Symptoms in Children Phase 2 A00315 Completed NCT00520754 PDF Cranswick et al. Int J Clin Pharmacol Ther;2005;43(4);172-177. Allergic Rhinitis Efficacy and Safety of Levocetirizine and Fexofenadine in Reducing Symptoms of Seasonal Allergic Rhinitis Phase 4 A00324 Completed NCT00542607 PDF Horak et al. Br J Clin Pharmacol;2005;60(1);24-31. Allergic Rhinitis Evaluation of Efficacy and Safety of Levocetirizine to Subjects With Perennial Allergic Rhinitis to House Dust Mites Phase 4 A00333 Completed NCT00521131 PDF "Didier. Eur Respir J;2004;24;Suppl 48;124S. 14th ERS (European Respiratory Society) Annual Congress, September 4-8, 2004;Glasgow, UK." Urticaria Study to Compare the Efficacy and Safety Between Levocetirizine and Loratadine for Chronic Idiopathic Urticaria Phase 3 A00334 Completed NCT00525382 PDF Allergic Rhinitis To Evaluate the Efficacy and Safety of Levocetirizine Versus Loratadine for Treatment of Seasonal Allergic Rhinitis Phase 3 A00348 Completed NCT00525278 PDF Allergic Rhinitis Efficacy and Safety of Levocetirizine Versus Loratadine for the Treatment of Perennial Allergic Rhinitis Phase 3 A00349 Completed NCT00524836 PDF Allergic Rhinitis Efficacy of Levocetirizine and Cetirizine in Reducing Symptoms of Seasonal Allergic Rhinitis in Ragweed Sensitive Subjects Phase 3 A00379 Completed NCT00544388 PDF Allergy Facial Thermography Study of Levocetirizine Versus Cetirizine Phase 4 A00380 Completed NCT00150761 PDF Asthma Prevention of Asthma With Levocetirizine (36 Month Treatment) in Young Children Suffering From Eczema (Atopic Dermatitis) and Sensitized to Grass Pollen and House Dust Mite and Having Completed the Previous EPAAC Trial (NCT00152464) Phase 3 A00384 Terminated NCT00160563 LINK Allergic Rhinitis Open Study to Evaluate the Safety of Levocetirizine in Young Children (2 - 6 Years) Suffering From Allergic Rhinitis Phase 2 A00385 Completed NCT00152412 PDF Allergic Rhinitis POPULAR (Preference Of Patient Using Levocetirizine in Allergic Rhinitis) Phase 4 A00391 Completed NCT001605372004-002971-18 LINK PDF Allergic Rhinitis ATAREAL (Antihistamine Treatment for Allergic Rhinitis in Real Life) Phase 4 A00392 Completed NCT001606802004-003858-26 LINKLINK PDF Canonica et al. Curr Med Res Opin;2008;24(10);2829-2839. Urticaria CUTE (Chronic Urticaria Treatment Evaluation) Phase 4 A00394 Completed NCT002643032005-000358-65 LINKLINK Potter et al. Allergy;2009;64(4);596-604. Allergic Rhinitis LEADER (LEvocetirizine And DEsloratadine in Allergic Rhinitis) Phase 4 A00401 Completed NCT001605892004-002823-42 LINK PDF Dermatitis - Eczema Randomized Phase III Study to Evaluate the Efficacy and Safety of Xyzal® (Levocetirizine) vs Zyrtec® (Cetirizine) in Subjects With Dermatitis and Eczema Phase 3 A00410 Completed NCT00375713 LINK Allergic Rhinitis Compare the Efficacy of Levocetirizine to Placebo in Reducing Symptoms of SAR in Sensitive Subjects Exposed to Ragweed Pollen Phase 2 A00412 Completed NCT00291642 LINK PDF Allergy Rhinitis Compare the Efficacy of Levocetirizine and Montelukast to Placebo in Reducing SAR Symptoms in Ragweed Sensitive Subjects Phase 4 A00414 Completed NCT00295022 LINK PDF Day et al. Allerg Asthma Proc;2008;29(3);304-312. Allergy Rhinitis Compare the Efficacy of Levocetirizine to Montelukast in Reducing Symptoms of SAR in Sensitive Subjects Exposed to Ragweed Pollen Phase 3 A00415 Completed NCT00315523 PDF Patel & Patel. Ann Allergy Asthma Immunol;2008;101(3);287-294. Allergy Evaluation of Treatment Satisfaction in Children With an Allergy and Who Received an Antihistamine Phase 4 A00420 Completed NCT00453583 PDF Ferrer et al. Clin Drug Investig. 2010;30(1);15-34. Allergic Rhinitis Safety Study of Levocetirizine Dihydrochloride Oral Liquid Formulation in Children Aged 6 Months to 11 Months Phase 3 A00423 Completed NCT006281082007-003458-28 LINKLINK Hampel et al. Allergy Asthma Proc;2010;31(4);290-295. Allergic Rhinitis Safety Study of Levocetirizine Dihydrochloride Oral Liquid Formulation in Children Aged 1 to Less Than 6 Years Suffering From Allergic Rhinitis or Chronic Urticaria of Unknown Origin Phase 3 A00426 Completed NCT006198012015-000205-39 LINKLINK Hampel et al. Allergy Asthma Proc;2010;31(4);290-295. Allergic Rhinitis A Study Evaluating the Efficacy and Impact on Health-related Quality of Life of Levocetirizine in Adults With Seasonal Allergic Rhinitis Phase 4 A00430 Completed NCT00621959 LINK Segall et al. Ann Allergy Asthma Immunol;2010;104(3);259-267. Allergic Rhinitis A Study Evaluating the Efficacy and Impact on Health-related Quality of Life of Levocetirizine in Adults With Seasonal Allergic Rhinitis Phase 4 A00431 Completed NCT00653224 LINK Segall et al. Ann Allergy Asthma Immunol;2010;104(3);259-267.
